Single-cell atlases
Building large-scale single-cell profiles of tumors to define cell states, lineage programs, and resistance mechanisms.
Research
Our lab develops integrative approaches to dissect the molecular landscape of brain tumors using single-cell and multi-modal data. We study how immune, neuron, and tumor cells interact, and we translate each patient’s molecular signature into tractable therapeutic hypotheses.
Brain tumor microenvironments
Resolving cellular neighborhoods to understand tumor evolution, immune suppression, and treatment response.
Patient-specific targets
Identifying actionable genes, drug candidates, and pathways to guide individualized treatment.
We are especially interested in projects that connect method development with translational questions in neurosurgery and neuro-oncology.